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Description
1 Scott, R.J., Palmer, J., Lewis, I.A.S., et al. Determination of a «GW cocktail» of cytochrome P450 probe substrate and their metabolites in plasma and urine using automated solid phase extraction and fast gradient liquid chromatography tandem mass spectrometry. Rapid Commun Mass Spectrom 13 2305-2319 (1999).
2 Frye, R.F., Adedoyin, A., Mauro, K., et al. Use of chlorzoxazone as an in vivo probe of cytochrome P450 2E1: Choice of dose and phenotypic trait measure. J Clin Pharmacol 38 82-89 (1998).
3 Court, M.H., Von Moltke, L.L., Shader, R.I., et al. Biotransformation of chlorzoxazone by heptic microsomes from humans and ten other mammalian species. Biopharm Drug Dispos 18 213-226 (1997).
4 Peter, R., Bocker, R., Beaune, P.H., et al. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P450 2E1. Chem Res Toxicol 3 566-573 (1990).
| Synonyms |
|
|---|---|
| Formal Name | 5-chloro-6-hydroxy-2(3H)-benzoxazolone |
| CAS Number | 1750-45-4 |
| Molecular Formula | C7H4ClNO3 |
| Formula Weight | 185.6 |
| Formulation | A crystalline solid |
| Purity | ≥97% |
| λmax | 301 nm |
| Stability | 1 year |
| Storage | -20°C |
| Shipping | Wet ice in continental US; may vary elsewhere |
| SMILES |
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Background Reading
Scott, R.J., Palmer, J., Lewis, I.A.S., et al. Determination of a «GW cocktail» of cytochrome P450 probe substrate and their metabolites in plasma and urine using automated solid phase extraction and fast gradient liquid chromatography tandem mass spectrometry. Rapid Commun Mass Spectrom 13 2305-2319 (1999).
Court, M.H., Von Moltke, L.L., Shader, R.I., et al. Biotransformation of chlorzoxazone by heptic microsomes from humans and ten other mammalian species. Biopharm Drug Dispos 18 213-226 (1997).
Peter, R., Bocker, R., Beaune, P.H., et al. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P450 2E1. Chem Res Toxicol 3 566-573 (1990).
Frye, R.F., Adedoyin, A., Mauro, K., et al. Use of chlorzoxazone as an in vivo probe of cytochrome P450 2E1: Choice of dose and phenotypic trait measure. J Clin Pharmacol 38 82-89 (1998).
Show all 4 Hide all but first 3| Size | Price | Quantity | Subtotal |
|---|---|---|---|
| 5 mg | $168.00 | $0.00 | |
| Bulk | Contact | ||
| Cart Total | $0.00 |
This product is available in custom sizes and/or larger quantities.
Please contact our Sales Department for a quote or to purchase.
Pricing updated 2012-02-12. Prices are subject to change without notice.
To ask for assistance with one of our products please contact a Technical Support Scientist.
Warning This product is not for human or veterinary use.
Downloads
 | Download Product Insert 168 Kb PDF |
| Download Material Safety Data Sheet (MSDS) 49 Kb PDF |
|
Printer-friendly version of this page small PDF (usually less than 100 Kb) |
| • US Letter paper 8½″ × 11″ | |
| • A4 paper 21cm × 29.7cm | |
| Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details. |
Batch-specific Information
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.
Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA
Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640
Copyright 2012 Cayman Chemical Company
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