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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

CAY10506 Exclusive

Cayman Chemical Item Number 10009079

(CAS 292615-75-9)

CAY10506 (CAS 292615-75-9)

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Description

Anti-diabetic drugs of the thiazolidinedione (TZD) structural class as well as α-lipoic acid activate peroxisome proliferator-activated receptor γ (PPARγ), a nuclear transcription factor that controls glucose metabolism and lipid homeostasis. CAY10506 is a hybrid lipoic acid-TZD derivative that transactivates human PPARγ with an EC50 value of 10 µM.1

1 Chittiboyina, A.G., Venkatraman, M.S., Mizuno, C.S., et al. Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARγ agonists. J Med Chem 49 4072-4084 (2006).

Formal Name N-​[2-​[4-​[(2,​4-​dioxo-​5-​thiazolidinyl)methyl]phenoxy]ethyl]-​1,​2-​dithiolane-​3-​pentanamide
CAS Number 292615-75-9
Molecular Formula C20H26N2O4S3
Formula Weight 454.6
Formulation A solution in methyl acetate
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O=C(CCCCC1SSCC1)​NCCOc1ccc(cc1)​CC1SC(=O)​NC1=O

Background Reading

Chittiboyina, A.G., Venkatraman, M.S., Mizuno, C.S., et al. Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARγ agonists. J Med Chem 49 4072-4084 (2006).
Size Price Quantity Subtotal
1 mg $35.00 $0.00
5 mg $158.00 $0.00
10 mg $280.00 $0.00
50 mg $1,225.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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