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GSK3β (Phospho-Ser⁹) Polyclonal Antibody

Cayman Chemical Item Number 10009374

Anti-Phospho-Ser⁹ Glycogen Synthase Kinase 3β

See more	Western Blot (557) Antibodies (630) Diabetes (134)

Description

Antigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser⁹ of GSK3β · Host: rabbit · Application(s): WB · Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that is involved in the regulation of many signaling pathways. To date, two isoforms have been identified: GSK3α and GSK3β. Specifically, GSK3β has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways. It has been suggested that Ser⁹ phosphorylation underlies the inhibition of GSK3β by insulin.

Synonyms

Anti-Phospho-Ser9 Glycogen Synthase Kinase 3β

Formulation

Peptide affinity-purified antibody

Stability

1 year

Storage

-20°C

Shipping

Wet ice in continental US; may vary elsewhere

Specificity

Rat GSK3β	+
Human GSK3β (expected)	+
Mouse GSK3β (expected)	+
Chicken GSK3β (expected)	+
Canine GSK3β (expected)	+
Non-human primate GSK3β (expected)	+
Zebrafish GSK3β (expected)	+
Xenopus GSK3β (expected)	+

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Background Reading

Sutherland, C., Leighton, I.A., and Cohen, P. Inactivation of glycogen synthase kinase 3β by phosphorylation: New kinase connections in insulin and growth-factor signaling. Biochem J 296(Pt. 1) 15-19 (1993).

Papkoff, J., and Aikawa, M. WNT-1 and HGF regulate GSK3β activity and β-catenin signaling in mammary epithelial cells. Biochem Biophys Res Commun 247(3) 851-858 (1998).

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Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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Batch-specific Information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

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GSK3β (Phospho-Ser9) Polyclonal Antibody