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10009411 Ribosomal S6 Kinase 2 Polyclonal Antibody
RSK2
Ribosomal S6 Kinase 2 Polyclonal Antibody Workbook Links
Cayman offers a variety of analysis tools to assist you.
Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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Antigen:
peptide corresponding to amino acid residues from the C-terminal region of rat RSK2
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Host:
rabbit
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Application(s):
WB
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The p90 ribosomal S6 kinases (RSK) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits.1 Recent work suggests that RSK2 exerts a tonic regulation on G protein-coupled signalling.2
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1
Hanauer, A., Young, I.D. Coffin-Lowry syndrome: Clinical and molecular features. J Med Genet 39 705-713 (2002).
2
Sheffler, D.J., Kroeze, W.K., Garcia, B.G., et al. p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling. Proc Natl Acad Sci USA 103 4717-4722 (2006).
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Purchase 10009411 Ribosomal S6 Kinase 2 Polyclonal Antibody
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
Please contact our
Sales Department
for a quote or to purchase.
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To ask for assistance with one of our products please contact our Technical Help staff.
Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-15.
Prices are subject to change without notice.
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