10009431 1-Stearoyl-2-Arachidonoyl PC-d8
SAPC-d8; 1-Stearoyl-2-Arachidonoyl Phosphatidylcholine-d8
1-Stearoyl-2-Arachidonoyl PC-d8 Workbook Links
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Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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1-Stearoyl-2-Arachidonoyl PC-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of SAPC by GC- or LC-mass spectrometry. Oxidation of phospholipids in low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.1 1-stearoyl-2-arachidonoyl-sn-Glycero-3-phosphocholine (SAPC) is one of the major phospholipid species in LDL. Upon oxidation, SAPC that been shown to induce monocyte-endothelial interactions.2
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1
Milne, G.L., Seal, J.R., Havrilla, C.M., et al. Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins. J Lipid Res 46 307-319 (2005).
2
Subbanagounder, G., Leitinger, N., Schwenke, D.C., et al. Determinants of bioactivity of oxidized phospholipids: Specific oxidized fatty acyl groups at the sn-2 position. Arterioscler Thromb Vasc Biol 20 2248-2254 (2000).
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Purchase 10009431 1-Stearoyl-2-Arachidonoyl PC-d8
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-18.
Prices are subject to change without notice.
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