See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

1-Stearoyl-2-Arachidonoyl PC-d8 Exclusive

Cayman Chemical Item Number 10009431

SAPC-d8; 1-Stearoyl-2-Arachidonoyl Phosphatidylcholine-d8

1-Stearoyl-2-Arachidonoyl PC-d8

See more

Description

1-Stearoyl-2-Arachidonoyl PC-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of SAPC by GC- or LC-mass spectrometry. Oxidation of phospholipids in low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.1 1-stearoyl-2-arachidonoyl-sn-Glycero-3-phosphocholine (SAPC) is one of the major phospholipid species in LDL. Upon oxidation, SAPC that been shown to induce monocyte-endothelial interactions.2

1 Milne, G.L., Seal, J.R., Havrilla, C.M., et al. Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins. J Lipid Res 46 307-319 (2005).

2 Subbanagounder, G., Leitinger, N., Schwenke, D.C., et al. Determinants of bioactivity of oxidized phospholipids: Specific oxidized fatty acyl groups at the sn-2 position. Arterioscler Thromb Vasc Biol 20 2248-2254 (2000).

Synonyms
  • SAPC-d8
  • 1-Stearoyl-2-Arachidonoyl Phosphatidylcholine-d8
Formal Name 1-​ocatadeconyl-​2R-​(5Z,​8Z,​11Z,​14Z-​eicosatetraenoyl)-​sn-​glyceryl-​3-​phosphorylcholine-​5,​6,​8,​9,​11,​12,​14,​15-​d14
Molecular Formula C46H76D8NO8P
Formula Weight 818.2
Formulation A solution in ethanol
Purity 99% deuterated product
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
[O-]​P(OC[C@H]​(OC(CCC/C([2H]​)​=C([2H]​)​\C/C([2H]​)​=C([2H]​)​\C/C([2H]​)​=C([2H]​)​\C/C([2H]​)​=C([2H]​)​\CCCCC)​=O)​COC(CCCCCCCCCCCCCCCCC)​=O)​(OCC[N+]​(C)​(C)​C)​=O

Background Reading

Subbanagounder, G., Leitinger, N., Schwenke, D.C., et al. Determinants of bioactivity of oxidized phospholipids: Specific oxidized fatty acyl groups at the sn-2 position. Arterioscler Thromb Vasc Biol 20 2248-2254 (2000).

Milne, G.L., Seal, J.R., Havrilla, C.M., et al. Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins. J Lipid Res 46 307-319 (2005).
Size Price Quantity Subtotal
50 µg $43.00 $0.00
100 µg $82.00 $0.00
500 µg $344.00 $0.00
1 mg $602.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

1,2-bis(heptanoylthio) Glycerophosphocholine
1-Stearoyl-2-Arachidonoyl PC

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?