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1,2-dipalmitoyl-sn-glycero-3-PC

Cayman Chemical Item Number 10009473

L-dipalmitoyl Lecithin; L-DPPC; 1,2-dipalmitoyl-sn-glycero-3-Phosphatidylcholine (CAS 63-89-8)

1,2-dipalmitoyl-sn-glycero-3-PC (CAS 63-89-8)

See more	Phospholipids (58) Alzheimer's Research (44) Neuroscience (654)

Description

1,2-dipalmitoyl-sn-glycero-3-PC (L-DPPC) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. The extent of incorporation of the enzyme γ-glutamyl transpeptidase in erythrocyte membranes was five times higher when proteoliposomes were prepared from L-DPPC as compared to control.¹ L-DPPC incorporated liposomes have potential in establishing active immunotherapy with antigens exhibiting poor immunogenicity, such as glycosphingolipid antigens.²

1 Kalra, V.K., Sikka, S.C., and Sethi, G.S. Transport of amino acids in γ-glutamyl transpeptidase-implanted human erythrocytes. J Biol Chem 256(11) 5567-5571 (1981).

2 Uemura, A., Watarai, S., Iwasaki, T., et al. Induction of immune responses against glycosphingolipid antigens: Comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J Vet Med Sci 67(12) 1197-1201 (2005).

Synonyms	L-dipalmitoyl Lecithin L-DPPC 1,2-dipalmitoyl-sn-glycero-3-Phosphatidylcholine
Formal Name	1,2-dihexadecanoyl-sn-glycero-3-phosphorylcholine
CAS Number	63-89-8
Molecular Formula	C₄₀H₈₀NO₈P
Formula Weight	734.1
Formulation	A crystalline solid
Purity	>98%
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N](C)(C)C)OC(=O)CCCCCCCCCCCCCCC

Background Reading

Kalra, V.K., Sikka, S.C., and Sethi, G.S. Transport of amino acids in γ-glutamyl transpeptidase-implanted human erythrocytes. J Biol Chem 256(11) 5567-5571 (1981).

Uemura, A., Watarai, S., Iwasaki, T., et al. Induction of immune responses against glycosphingolipid antigens: Comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J Vet Med Sci 67(12) 1197-1201 (2005).

1,2-dipalmitoyl-sn-glycero-3-PC is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
25 mg	$25.00		$0.00
50 mg	$48.00		$0.00
100 mg	$90.00		$0.00
250 mg	$200.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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