Cayman Chemical | PSD95 Polyclonal Antibody | Description • Postsynaptic Density Protein of 95

10009506 PSD95 Polyclonal Antibody

Postsynaptic Density Protein of 95

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Antigen: peptide corresponding to amino acid residues from the N-terminal region of rat PSD95 · Host: rabbit · Application(s): WB · PSD95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses.¹ Recent work suggests that interaction of the NMDAR with PSD95 via these PDZ domains can be regulated by phosphorylation.²

1 Ye, B., Liao, D., Zhang, X., et al. GRASP-1: A neuronal RasGEF associated with the AMPA receptor/GRIP complex. Neuron 26 603-617 (2000).

2 Scannevin, R.H., Huganir, R.L. Postsynaptic organization and regulation of excitatory synapses. Nature Reviews 1 133-141 (2000).

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Pricing updated 2010-03-19.
Prices are subject to change without notice.

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