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10009551 FABP7 (human recombinant)
B-FABP; Brain-FABP; Fatty Acid Binding Protein 7
FABP7 (human recombinant) Workbook Links
Cayman offers a variety of analysis tools to assist you.
Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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Source:
recombinant N-terminal His-tagged protein expressed in E. coli
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Mr:
19 kDa
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Fatty Acid Binding Protein 7 (FABP7) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids.1 Members of this protein family exhibit high affinity for lipophilic ligands and were named according to the tissue from which they were initially isolated.1 Studies suggest that FABPs are involved in the uptake and metabolism of fatty acids, in the maintenance of cellular fatty acid levels, in intracellular trafficking of these substrates, in the modulation of specific enzymes of lipid metabolic pathways, and in the modulation of cell growth and differentiation.2 FABP family members have highly conserved three dimensional structures and 22-73% amino acid sequence similarity. FABP7 is composed of ten antiparallel β strands that form a barrel. It is exclusively expressed in the central nervous system where its main function is possibly the binding and transport of polyunsaturated fatty acids like docosahexaenoic acid.1
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1
Zimmerman, A.W., Veerkamp, J.H. New insights into the structure and function of fatty acid-binding proteins. Cell Mol Life Sci 59 1096-1116 (2002).
2
Massolini, G., Calleri, E. Survey of binding properties of fatty acid-binding proteins chromatographic methods. J Chromatogr B 797 255-268 (2003).
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Purchase 10009551 FABP7 (human recombinant)
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-14.
Prices are subject to change without notice.
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