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10009624 COX-2 (human) Western Ready Control
Cyclooxygenase-2; Prostaglandin H Synthase 2
COX-2 (human) Western Ready Control Workbook Links
Cayman offers a variety of analysis tools to assist you.
Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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Application(s):
positive control for WB
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Source:
human recombinant N-terminal His-tagged protein expressed in Sf21 cells
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Mr:
73 kDa (His-tagged), 70 kDa (native)
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Cyclooxygenase-2 (COX-2) catalyzes the first step in the biosynthesis of PGs, thromboxanes, and prostacyclins: the conversion of arachidonic acid to PGH2. Recent discoveries of the induction of the COX expression by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of COX, COX-2, is responsible for the biosynthesis of prostaglandins under acute inflammatory conditions. 1 Thus, COX-2 has become the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development.
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1
Xie, W., Chipman, J.G., Robertson, D.L., et al. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 88 2692-2696 (1991).
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Purchase 10009624 COX-2 (human) Western Ready Control
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
Please contact our
Sales Department
for a quote or to purchase.
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-17.
Prices are subject to change without notice.
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