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Prostaglandin E Synthase (cytosolic) Western Ready Control

Cayman Chemical Item Number 10009735

Hsp 90 Co-chaperone; p23; cPGE Synthase; cPGES; Telomerase-binding protein p23

Prostaglandin E Synthase (cytosolic) Western Ready Control

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Description

Application(s): positive control for WB · Source: human recombinant protein expressed in E.coli · Mr: 18 kDa · Prostaglandin E synthase (PGES) catalyzes the isomerization of PGH2 to PGE2. Cytosolic and microsomal PGES enzymes have been cloned and characterized. Cytosolic PGES (cPGES) is a glutathione-dependent enzyme with a predicted size of 18.6 kDa. The enzyme is expressed in a variety of tissues and cells, the levels of which are unaffected by treatment with interleukin-1β and TNF-α.1 However, enzyme expression increases approximately 3-fold in rat brain following lipopolysaccharide treatment.1

1 Tanioka, T., Nakatani, Y., Semmyo, N., et al. Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 immediate prostaglandin E2 biosynthesis. J Biol Chem 275 32775-32782 (2000).

Synonyms
  • Hsp 90 Co-chaperone
  • p23
  • cPGE Synthase
  • cPGES
  • Telomerase-binding protein p23
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere

Background Reading

Tanioka, T., Nakatani, Y., Semmyo, N., et al. Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 immediate prostaglandin E2 biosynthesis. J Biol Chem 275 32775-32782 (2000).
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1 ea $51.00 $0.00
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Pricing updated 2012-05-25. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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