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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

17(S)-HDoHE

Cayman Chemical Item Number 10009799

17(S)-hydroxy Docosahexaenoic Acid

17(S)-HDoHE

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Description

17(S)-HDoHE is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and murine brain.1 17(S)-HDoHE serves as a precursor to 17(S)-resolvins and has intrinsic biological activity, such as the inhibition of TNFα-induced interleukin-1β expression in human glioma cells and inhibition of TNFα-induced leukocyte trafficking to the murine air pouch.1

1 Hong, S., Gronert, K., Devchand, P.R., et al. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J Biol Chem 278(17) 14677-14687 (2003).

Synonyms
  • 17(S)-hydroxy Docosahexaenoic Acid
Formal Name 17S-​hydroxy-​4Z,​7Z,​10Z,​13Z,​15E,​19Z-​docosahexaenoic acid
Molecular Formula C22H32O3
Formula Weight 344.5
Formulation A solution in ethanol
Purity ≥98%
Stability 2 years
Storage -20°C
SMILES
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CC/C=C\CC(O)​\C=C\C=C\C/C=C\C/C=C\C/C=C\CCC(=O)​O

Background Reading

Hong, S., Gronert, K., Devchand, P.R., et al. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J Biol Chem 278(17) 14677-14687 (2003).
Size Price Quantity Subtotal
25 µg $92.00 $0.00
50 µg $175.00 $0.00
100 µg $331.00 $0.00
250 µg $736.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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