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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

1,2-Dioctanoyl PC

Cayman Chemical Item Number 10009874

1,2-Dioctanoyl Phosphatidylcholine (CAS 19191-91-4)

1,2-Dioctanoyl PC (CAS 19191-91-4)

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Description

Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Dioctanoyl PC is a synthetic analog of natural phosphatidylcholine species containing saturated C8:O fatty acids in the sn-1 and sn-2 positions of the glycerol backbone. It exhibits a critical micelle concentration (CMC) value of 0.25 mM at 27°C.1 1,2-Dioctanoyl PC serves as an efficient substrate for phospholipase D (PLD) as well as sPLA2 isozymes from bovine pancreas and bee venom.2,3

1 missing reference text

2 Davis, L.L., Maglio, J.J., and Horwitz, J. Phospholipase D hydrolyzes short-chain analogs of phosphatidylcholine in the absence of detergent. Lipids 33 223-227 (1998).

3 Lin, G., Noel, J., Loffredo, W., et al. Use of short-chain cyclopentano-phosphatidycholines to probe the mode of activation of phospholipase A2 from bovine pancreas and bee venom. J Biol Chem 263(26) 13208-13214 (1988).

Synonyms
  • 1,2-Dioctanoyl Phosphatidylcholine
Formal Name 1,​2-​bis(O-​octanoyl)-​sn-​glyceryl-​phophorylcholine
CAS Number 19191-91-4
Molecular Formula C24H48NO8P
Formula Weight 509.6
Formulation A solution in ethanol
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCCCCC(=O)​OC[C@H]​(COP(=O)​([O-]​)​OCC[N+]​(C)​(C)​C)​OC(=O)​CCCCCCC

Background Reading

Lin, G., Noel, J., Loffredo, W., et al. Use of short-chain cyclopentano-phosphatidycholines to probe the mode of activation of phospholipase A2 from bovine pancreas and bee venom. J Biol Chem 263(26) 13208-13214 (1988).

Size Price Quantity Subtotal
5 mg $11.00 $0.00
10 mg $21.00 $0.00
25 mg $50.00 $0.00
50 mg $88.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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