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1,2-Didecanoyl PC

Cayman Chemical Item Number 10009879

1,2-Didecanoyl Phosphatidylcholine; Didecanoyl Lecithin (CAS 3436-44-0)

1,2-Didecanoyl PC (CAS 3436-44-0)

See more	Eicosanoids (216) Fatty Acids (267) Lipid Mediators (47)

Description

Phosphatidylcholine species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Didecanoyl PC is a synthetic, less hydrophobic phospholipis that has been found to be useful for enhancing the absorption of peptide drugs and hormones such as insulin. Thus, the bioavailability of intranasally applied human growth hormone is enhanced when coadministered with the absorption enhancer 1,2-didecanoyl PC.¹

1 Agerholm, C., Bastholm, L., Johansen, P.B., et al. Epithelial transport and bioavailability of intranasally administered human growth hormone formulated with the absorption enhancers didecanoyl-L-a-phosphatidylcholine and a-cyclodextrin in rabbits. J Pharm Sci 83(12) 1706-1711 (1994).

Synonyms	1,2-Didecanoyl Phosphatidylcholine Didecanoyl Lecithin
Formal Name	1,2-bis(O-decanoyl)-sn-glyceryl-3-phosphorylcholine
CAS Number	3436-44-0
Molecular Formula	C₂₈H₅₆NO₈P
Formula Weight	565.7
Formulation	A solution in ethanol
Purity	≥98%
Stability	1 year
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N](C)(C)C)OC(=O)CCCCCCCCC

Background Reading

Agerholm, C., Bastholm, L., Johansen, P.B., et al. Epithelial transport and bioavailability of intranasally administered human growth hormone formulated with the absorption enhancers didecanoyl-L-a-phosphatidylcholine and a-cyclodextrin in rabbits. J Pharm Sci 83(12) 1706-1711 (1994).

1,2-Didecanoyl PC is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
5 mg	$11.00		$0.00
10 mg	$21.00		$0.00
25 mg	$50.00		$0.00
50 mg	$88.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

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Batch-specific Information

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