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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

CB-25 Exclusive

Cayman Chemical Item Number 10010116

(CAS 869376-63-6)

CB-25 (CAS 869376-63-6)

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Description

CB-25 is a stable analog of Δ9-tetrahydrocannabinol (THC) and anandamide (AEA). It exhibits high affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 5.2 and 13 nM, respectively. CB-25 behaves as an inverse agonist for the CB1 receptor as assessed in a cyclic AMP (cAMP) functional assay.1,2

1 Brizzi, A., Brizzi, V., Cascio, M.G., et al. Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors. J Med Chem 48 7343-7350 (2005).

2 Cascio, M.G., Bisogno, T., Palazzo, E., et al. In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands. Br J Pharmacol 149 431-440 (2006).

Formal Name N-​cyclopropyl-​11-​(3-​hydroxy-​5-​pentylphenoxy)-​undecanamide
CAS Number 869376-63-6
Molecular Formula C25H41NO3
Formula Weight 403.6
Formulation A crystalline solid
Purity >98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCc1cc(OCCCCCCCCCCC(=O)​NC2CC2)​cc(O)​c1

Background Reading

Brizzi, A., Brizzi, V., Cascio, M.G., et al. Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors. J Med Chem 48 7343-7350 (2005).

Cascio, M.G., Bisogno, T., Palazzo, E., et al. In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands. Br J Pharmacol 149 431-440 (2006).

CB-25 is available in the following screening library:

Size Price Quantity Subtotal
1 mg $19.00 $0.00
5 mg $86.00 $0.00
10 mg $152.00 $0.00
50 mg $665.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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