Cayman Chemical | AM1241 | Description (CAS 444912-48-5)

10010118 AM1241

(CAS 444912-48-5)

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• See more Cannabinoids; Neuroscience; Pain

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AM1241 is a peripheral cannabinoid (CB₂) receptor agonist with a K_i value of 2 nM and greater than 100-fold selectivity over the central cannabinoid (CB₁) receptor in vitro.¹ AM1241 produces antinociception to thermal stimuli in rat hindpaw. The antinociceptive actions of AM1241 were blocked by the CB₂ receptor-selective antagonist AM630 but not by the CB₁ receptor-selective antagonist AM251 (Catalog No. 71670).¹

1 Malan, T.P., Ibrahim, M.M., Deng, H., et al. CB₂ cannabinoid receptor-mediated peripheral antinociception. Pain 93 239-245 (2001).

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Pricing updated 2010-03-20.
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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.