Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals.1 The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug.2
CAY10532 is a methyl ester analog of fluprostenol.
1
Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F2α. Nature250330-331(1974).
2
Sorbera, L.A., and Castañer, J. Travoprost. Drugs Future2541-45(2000).
Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F2α. Nature250330-331(1974).
Sorbera, L.A., and Castañer, J. Travoprost. Drugs Future2541-45(2000).
deLong, M.A., Mciver, J.M., and Youngquist, S.R. Compositions and methods for treating hair loss using non-naturally occurring prostaglandins. PCT/US01/103701-72(2001).
Fluprostenol methyl ester is available in the following screening
library: