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1-Hexadecyl Lysophosphatidic Acid

Cayman Chemical Item Number 10010188

AGP 16:0; 1-Hexadecyl-2-hydroxy-sn-glycero-3-phosphate; Alkyl glycero phosphate 16:0 (CAS 52603-03-9)

1-Hexadecyl Lysophosphatidic Acid (CAS 52603-03-9)

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Description

1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.1 LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.2,3

1 Tsukahara, T., Tsukahara, R., Yasuda, S., et al. Different residues mediate recognition of 1-O-oleyl-lysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor γ. J Biol Chem 281(6) 3398-3407 (2006).

2 Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions. Trends Cell Biol 4 213-219 (1994).

3 Chun, J., Goetzl, E.J., Hla, T., et al. International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacol Rev 54 265-269 (2002).

Synonyms
  • AGP 16:0
  • 1-Hexadecyl-2-hydroxy-sn-glycero-3-phosphate
  • Alkyl glycero phosphate 16:0
Formal Name 3-​(hexadecyloxy)-​1-​(dihydrogen phosphate)-​1,​2R-​propanediol
CAS Number 52603-03-9
Molecular Formula C19H41O6P
Formula Weight 396.5
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCCOC[C@@H]​(O)​COP(O)​(O)​=O

Background Reading

Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions. Trends Cell Biol 4 213-219 (1994).

Chun, J., Goetzl, E.J., Hla, T., et al. International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacol Rev 54 265-269 (2002).

Tsukahara, T., Tsukahara, R., Yasuda, S., et al. Different residues mediate recognition of 1-O-oleyl-lysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor γ. J Biol Chem 281(6) 3398-3407 (2006).

1-Hexadecyl Lysophosphatidic Acid is available in the following screening library:

Size Price Quantity Subtotal
1 mg $31.00 $0.00
5 mg $140.00 $0.00
10 mg $248.00 $0.00
25 mg $543.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-25. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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