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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide

Cayman Chemical Item Number 10010405

15-keto-Bimatoprost; 17-phenyl trinor PGF2α ethyl amide

15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide

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Description

Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug.1 Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2α ethyl amide. 15-keto-17-phenyl trinor PGF2α ethyl amide is a potential metabolite of 17-phenyl trinor PGF2α ethyl amide when 17-phenyl trinor PGF2α ethyl amide is administered to intact animals. No pharmacological studies on 15-keto-17-phenyl trinor PGF2α ethyl amide have been reported.

1 Woodward, D.F., Krauss, A.H., Chen, J., et al. The pharmacology of Bimatoprost (Lumigan™). Surv Ophthalmol 45 S337-S345 (2001).

Synonyms
  • 15-keto-Bimatoprost
  • 17-phenyl trinor PGF2α ethyl amide
Formal Name N-​ethyl-​9α,​11α-​dihydroxy-​15-​keto-​17-​phenyl-​18,​19,​20-​trinor-​prost-​5Z,​13E-​dien-​1-​amide
Molecular Formula C25H35NO4
Formula Weight 413.5
Formulation A solution in methyl acetate
Purity >98%
λmax 234 nm
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCNC(=O)​CCC/C=C\C[C@H]​1[C@@H]​(O)​C[C@@H]​(O)​[C@@H]​1\C=C\C(=O)​CCc1ccccc1

Background Reading

Woodward, D.F., Krauss, A.H., Chen, J., et al. The pharmacology of Bimatoprost (Lumigan™). Surv Ophthalmol 45 S337-S345 (2001).

15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide is available in the following screening library:

Size Price Quantity Subtotal
1 mg $50.00 $0.00
5 mg $225.00 $0.00
10 mg $400.00 $0.00
25 mg $875.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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