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Fluprostenol methyl amide Exclusive

Cayman Chemical Item Number 10010406

Fluprostenol methyl amide

See more	Prostaglandins (513) Ophthalmology (61)

Description

Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals.¹ The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug.² Fluprostenol is the optically active enantiomer of fluprostenol and would be expected to have twice the potency as the racemic mixture. Fluprostenol methyl amide is a methyl amide analog of fluprostenol. There are no published reports on the biological activity of fluprostenol methyl amide.

1 Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F_2α. Nature 250 330-331 (1974).

2 Sorbera, L.A., and Castañer, J. Travoprost. Drugs Future 25 41-45 (2000).

Formal Name	N-methyl-9α,11α,15R-trihydroxy-16-(3-(trifluoromethyl)phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-amide
Molecular Formula	C₂₄H₃₂F₃NO₅
Formula Weight	471.5
Formulation	A solution in ethanol
Purity	≥98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CNC(=O)CCC/C=C\CC1C(O)CC(O)[C@@H]1\C=C\C(O)COc1cccc(c1)C(F)(F)F

Background Reading

Sorbera, L.A., and Castañer, J. Travoprost. Drugs Future 25 41-45 (2000).

Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F_2α. Nature 250 330-331 (1974).

Size	Price	Quantity	Subtotal
1 mg	$51.00		$0.00
5 mg	$230.00		$0.00
10 mg	$408.00		$0.00
50 mg	$1,785.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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Batch-specific Information

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