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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

13,14-dihydro-15-keto Prostaglandin D1 Exclusive

Cayman Chemical Item Number 10010425

13,14-dihydro-15-keto PGD1

13,14-dihydro-15-keto Prostaglandin D1

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Description

Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2.1 13,14-dihydro-15-keto PGD1 is the theoretical metabolite of PGD1 via the 15-hydroxy PG dehydrogenase metabolic pathway. No biological studies for this compound have been reported.

1 Bundy, G.L., Morton, D.R., Peterson, D.C., et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. J Med Chem 26 790-799 (1983).

Synonyms
  • 13,14-dihydro-15-keto PGD1
Formal Name 9α-​hydroxy-​11,​15-​dioxo-​prost-​1-​oic acid
Molecular Formula C20H34O5
Formula Weight 354.5
Formulation A solution in methyl acetate
Purity >98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCCC(=O)​CC[C@H]​1C(=O)​CC(O)​C1CCCCCCC(=O)​O

Background Reading

Bundy, G.L., Morton, D.R., Peterson, D.C., et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. J Med Chem 26 790-799 (1983).

13,14-dihydro-15-keto Prostaglandin D1 is available in the following screening library:

Size Price Quantity Subtotal
1 mg $91.00 $0.00
5 mg $410.00 $0.00
10 mg $728.00 $0.00
50 mg $3,185.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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