See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Vialinin A

Cayman Chemical Item Number 10010519

Terrestrin A (CAS 858134-23-3)

Vialinin A (CAS 858134-23-3)

See more

Description

Vialinin A is a terphenyl compound originally isolated from the fungi T. terrestris 1 and T. vialis.2 Terphenyls, in general, are recognized as strong antioxidants.3 Vialinin A potently inhibits the release of TNF-α (IC50 = 0.09 nM) and IL-4 (IC50 = 2.8 nM), as well as β-hexosaminidase and CCL2 (MCP-1) from IgE-stimulated RBL-2H3 mast cells.4 Vialinin A does not significantly increase lactate dehydrogenase release from RBL-2H3 mast cells, suggesting low cytotoxicity.4

1 Radulovic, N., Quang, D.N., Hashimoto, T., et al. Terrestrins A-G: P-teraphenyl derivatives from the inedible mushroom Thelephora terrestris. Phytochem 66 1052-1059 (2005).

2 Xie, C., Koshino, H., Esumi, Y., et al. Vialinin A, a novel 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenger from an edible mushroom in china. Biosci Biotechnol Biochem 69(12) 2326-2332 (2005).

3 Liu, J. Natural terphenyls: Developments since 1877. Chem Rev 106 2209-2223 (2006).

4 Onose, J., Xie, C., Ye, Y.Q., et al. Vialinin A, a novel potent inhibitor of TNF-a production from RBL-2H3 cells. Biol Pharm Bull 31(5) 831-833 (2008).

Synonyms
  • Terrestrin A
Formal Name 4,​4”,​5’,​6’-​tetrahydroxy[1,​1’:4’,​1”-​terphenyl]-​2’,​3’-​diyl ester benzeneacetic acid
CAS Number 858134-23-3
Molecular Formula C34H26O8
Formula Weight 562.6
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
Oc1ccc(cc1)​c1c(OC(=O)​Cc2ccccc2)​c(OC(=O)​Cc2ccccc2)​c(c2ccc(O)​cc2)​c(O)​c1O

Background Reading

Onose, J., Xie, C., Ye, Y.Q., et al. Vialinin A, a novel potent inhibitor of TNF-a production from RBL-2H3 cells. Biol Pharm Bull 31(5) 831-833 (2008).

Xie, C., Koshino, H., Esumi, Y., et al. Vialinin A, a novel 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenger from an edible mushroom in china. Biosci Biotechnol Biochem 69(12) 2326-2332 (2005).

Liu, J. Natural terphenyls: Developments since 1877. Chem Rev 106 2209-2223 (2006).

Radulovic, N., Quang, D.N., Hashimoto, T., et al. Terrestrins A-G: P-teraphenyl derivatives from the inedible mushroom Thelephora terrestris. Phytochem 66 1052-1059 (2005).

Show all 4 Hide all but first 3
Size Price Quantity Subtotal
1 mg $46.00 $0.00
5 mg $207.00 $0.00
10 mg $368.00 $0.00
25 mg $805.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

Interleukin-4 (human) EIA Kit
TNF-α (human) EIA Kit

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?