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CAY10564 Exclusive

Cayman Chemical Item Number 10010527

4-(p-chlorophenyl)-1,3,2-Oxathiazolylium-5-olate

CAY10564

See more	NO Donors (26)

Description

S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10564 is a member of a new class of S-nitrosothiol species that act as an NO donors under acidic conditions. It decomposes with a half-life of one minute in 0.1 M phosphate buffer, pH 5.0, at 37°C and relaxes phenylephrine-constricted rat aortic strips 59% and 16% at pH 6.0 and 7.4, respectively.¹

1 Lu, D., Nadas, J., Zhang, G., et al. 4-Aryl-1,3,2-oxathiazolylium-5-olates as pH-controlled NO-donors: The next generation of S-nitrosothiols. J Am Chem Soc 129 5503-5514 (2007).

Synonyms	4-(p-chlorophenyl)-1,3,2-Oxathiazolylium-5-olate
Formal Name	4-chloro-4-phenyl-1,3,2-oxathiazolidine-5-one
Molecular Formula	C₈H₆ClNO₂S
Formula Weight	215.7
Formulation	A crystalline solid
Purity	>98%
λ_max	202, 262, 412 nm
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard Clc1ccc(cc1)C1[S]=NOC1O

Background Reading

Lu, D., Nadas, J., Zhang, G., et al. 4-Aryl-1,3,2-oxathiazolylium-5-olates as pH-controlled NO-donors: The next generation of S-nitrosothiols. J Am Chem Soc 129 5503-5514 (2007).

Size	Price	Quantity	Subtotal
5 mg	$25.00		$0.00
10 mg	$48.00		$0.00
25 mg	$113.00		$0.00
100 mg	$350.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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CAY10565

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Batch-specific Information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

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