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Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
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CAY10565

Cayman Chemical Item Number 10010528

4-(p-methoxyphenyl)-1,3,2-Oxathiazolylium-5-olate

CAY10565

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Description

S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10565 is a member of a new class of S-nitrosothiol species that act as NO donors under acidic conditions. It decomposes with a half-life of 130 minutes in 0.1 M phosphate buffer, pH 5.0, at 37°C and relaxes phenylephrine-constricted rat aortic strips 71% and 44% at pH 6.0 and 7.4, respectively.1

1 Lu, D., Nadas, J., Zhang, G., et al. 4-Aryl-1,3,2-oxathiazolylium-5-olates as pH-controlled NO-donors: The next generation of S-nitrosothiols. J Am Chem Soc 129 5503-5514 (2007).

Synonyms
  • 4-(p-methoxyphenyl)-1,3,2-Oxathiazolylium-5-olate
Formal Name 4-​methoxy-​4-​phenyl-​1,​3,​2-​oxathiazolidine-​5-​one
Molecular Formula C9H9NO3S
Formula Weight 211.2
Formulation A crystalline solid
Purity >95%
λmax 202, 268, 436 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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COc1ccc(cc1)​C1[S]​=NOC1O

Background Reading

Lu, D., Nadas, J., Zhang, G., et al. 4-Aryl-1,3,2-oxathiazolylium-5-olates as pH-controlled NO-donors: The next generation of S-nitrosothiols. J Am Chem Soc 129 5503-5514 (2007).
Size Price Quantity Subtotal
5 mg $25.00 $0.00
10 mg $48.00 $0.00
25 mg $113.00 $0.00
100 mg $350.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-25. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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