CD4 Monoclonal FITC Antibody (Clone RIV7)
Cayman Chemical Item Number 10010530
Description
Clone designation:
RIV7
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Host:
mouse
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Isotype:
IgG2a
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Application(s):
1 µg/ml for detection of CD4 by flow cytometry (FACS). Immunoblotting or staining paraffin-embedded tissue sections is not recommended with this antibody
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CD4, a transmembrane glycoprotein, is present on the surface of a majority of thymocytes and T cell subpopulations, which recognize antigens presented by MHC class II molecules. The CD4 antigen is also found on monocytes, dendritic cells, tissue macrophages and granulocytes. CD4+ T lymphocytes are presented by functional T-helper cells and CD4+CD25+ regulatory (suppressor) T cells. Estimation of CD4+ T cell level could be used for immunological status monitoring.1
1
Jonker, M., Nooij, F.J.M., Den Butter, G., et al. Side effects and immunogenicity of murine lymphocyte-specific monoclonal antibodies in subhuman primates. Transplantation 45(4) 677-682 (1988).
| Formulation |
50 µg IgG FITC conjugate |
| Stability |
1 year |
| Storage |
4°C |
| Shipping |
Wet ice
in continental US; may vary elsewhere
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| Specificity |
| Human CD4 Monoclonal FITC Antibody |
+ |
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Background Reading
Jonker, M., Nooij, F.J.M., Den Butter, G., et al. Side effects and immunogenicity of murine lymphocyte-specific monoclonal antibodies in subhuman primates. Transplantation 45(4) 677-682 (1988).
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Pricing updated 2012-02-12.
Prices are subject to change without notice.
To ask for assistance with one of our products please contact a Technical Support Scientist.
Warning This product is not for human or veterinary use.
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.
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