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Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday.
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Description
The second messengers cAMP and cGMP are important mediators of signal transduction and hence a wide range of cellular processes including vasodilation and synaptic plasticity. Type 2 cyclic nucleotide phosphodiesterases (PDE2) isoforms inactivate cAMP and cGMP by hydrolyzing the phosphodiester bond. BAY-
1 Boess, F.G., Hendrix, M., van der Staay, F., et al. Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance. Neuropharmacology 47 1081-1092 (2004).
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Masood, A., Nadeem, A., Mustafa, S.J., et al. Reversal of oxidative stress- 3 Rutten, K., Van Donkelaar, E.L., Ferrington, L., et al. Phosphodiesterase inhibitors enhance object memory independent of cerebral blood flow and glucose utilization in rats. Neuropsychopharmacology (2009).
Background ReadingBoess, F.G., Hendrix, M., van der Staay, F., et al. Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance. Neuropharmacology 47 1081-1092 (2004). Rutten, K., Van Donkelaar, E.L., Ferrington, L., et al. Phosphodiesterase inhibitors enhance object memory independent of cerebral blood flow and glucose utilization in rats. Neuropsychopharmacology (2009). Masood, A., Nadeem, A., Mustafa, S.J., et al. Reversal of oxidative stress-
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This product is available in custom sizes and/or larger quantities. Please contact our Sales Department for a quote or to purchase. Pricing updated 2012-05-25. Prices are subject to change without notice. To ask for assistance with one of our products please contact a Technical Support Scientist. Warning This product is not for human or veterinary use. Related Products
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640 Copyright 2012 Cayman Chemical Company | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||