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N-decanoyl-L-Homoserine lactone

Cayman Chemical Item Number 10011201

C₁₀-HSL (CAS 177315-87-6)

N-decanoyl-L-Homoserine lactone (CAS 177315-87-6)

See more	Lipids (167) Gene Regulation (173) Infectious Disease (64)

Description

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. A promising field of study involves controlling bacterial infections by quenching their quorum sensing systems. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-decanoyl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism.¹ The applications of this molecule include regulation of virulence and exoproteases.²

1 Barnard, A.M.L., and Salmond, G.P.C. Quorum sensing: The complexities of chemical communication between bacteria. Complexus 5(2) 87-101 (2004).

2 Williams, P. Quorum sensing, communication and cross-kingdom signalling in the bacterial world. Microbiology 153 3923-3938 (2007).

Synonyms	C10-HSL
Formal Name	N-[3S)-tetrahydro-2-oxo-3-furanyl]-decanamide
CAS Number	177315-87-6
Molecular Formula	C₁₄H₂₅NO₃
Formula Weight	255.4
Formulation	A crystalline solid
Purity	≥96%
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCCCC(=O)NC1CCOC1=O

Background Reading

Williams, P. Quorum sensing, communication and cross-kingdom signalling in the bacterial world. Microbiology 153 3923-3938 (2007).

Barnard, A.M.L., and Salmond, G.P.C. Quorum sensing: The complexities of chemical communication between bacteria. Complexus 5(2) 87-101 (2004).

Size	Price	Quantity	Subtotal
5 mg	$30.00		$0.00
10 mg	$57.00		$0.00
25 mg	$135.00		$0.00
50 mg	$240.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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