Cayman Chemical | Avenanthramide-C methyl ester | Description (CAS 955382-52-2)

10011336 Avenanthramide-C methyl ester

(CAS 955382-52-2)

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Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC₅₀ ~ 40 μM).¹ Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells. ¹

1 Guo, W., Wise, M.L., Collins, F.W., et al. Avenanthramides, polyphenols from oats, inhibit IL-1β-induced NF-κB activation in endothelial cells. Free Radic Biol Med 44 415-429 (2008).

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Purchase 10011336 Avenanthramide-C methyl ester

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Pricing updated 2010-03-19.
Prices are subject to change without notice.

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