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HDAC Activity Assay KitCayman Chemical Item Number 10011563 
HDAC Activity Assay Kit
Sold under license from Cyclex. Description
Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues resulting in chromatin condensation and transcriptional repression of chromosomal DNA. Thus, HDAC inhibition allows the conformation of DNA to be relaxed and transcriptional activation to ensue. Transcriptional repression of key genes has linked HDAC activity to cell growth and tumor development. Cayman’s HDAC Activity Assay Kit provides a fast, fluorescence-
Background ReadingGrunstein, M. Histone acetylation in chromatin structure and transcription. Nature 389 349-352 (1997 Sep 25). Johnstone, R.W. Histone- Cheung, W.L., Briggs, D.B., and Allis, C.D. Acetylation and chromosomal functions. Curr Opin Cell Biol 12 326-333 (2000 Jan 1). Kwon, H.J., Kim, M.S., Kim, M.J., et al. Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis. Int J Cancer 97 290-296 (2002 Jan 1). Strahl, B.D., and Allis, D. The language of covalent histone modifications. Nature 403 41-45 (2000 Jan 6). Suenaga, M., Soda, H., Oka, M., et al. Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells. Int J Cancer 97 621-625 (2002 Jan 1). Show all 6 Hide all but first 3 |
This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase. Pricing updated 2012-02-12. Prices are subject to change without notice. To ask for assistance with one of our products please contact a Technical Support Scientist. Warning This product is not for human or veterinary use. You may be eligible to receive a free sample HDAC Activity Assay Kit under the Cayman Challenge program. Let Cayman analyze your samples for you. See EIA Service for details and availability. Related ProductsShow all 11 Hide all but first 3Downloads
Batch-specific InformationLogin to access batch-specific information Sold under license from Cyclex. |
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins. |
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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA
Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640
Copyright 2012 Cayman Chemical Company
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