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10047 8-iso Misoprostol
8-iso Misoprostol Workbook Links
Cayman offers a variety of analysis tools to assist you.
Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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Misoprostol is a widely sold analog of prostaglandin E1 (PGE1) which has potent but relatively non-selective agonist activity with respect to the prostanoid EP receptor subgroup.1 Misoprostol has been used therapeutically for many years in humans for the treatment of gastric ulcer disease under the Searle tradename Cytotec.2 8-iso Misoprostol is one of several impurities which are possible in the production of bulk commercial preparations of misoprostol, and is somewhat difficult to distinguish from other impurities such as 11β-misoprostol.3 The pharmacology and EP receptor binding affinity for 8-iso misoprostol has not been published.
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1
Abramovitz, M., Adam, M., Boie, Y., et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483 285-293 (2000).
2
Collins, P.W. Misoprostol: Discovery, development, and clinical applications. Medicinal Research Reviews 10 149-172 (1990).
3
Iyer, R.R. Personal Communication. (2002).
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Purchase 10047 8-iso Misoprostol
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-19.
Prices are subject to change without notice.
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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.
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