See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

15-deoxy-Δ12,14-Prostaglandin A1

Cayman Chemical Item Number 10065

15-deoxy-Δ12,14-PGA1 (CAS 573951-20-9)

15-deoxy-Δ12,14-Prostaglandin A1 (CAS 573951-20-9)

See more

Description

15-deoxy-Δ12,14-Prostaglandin A1 (15-deoxy-Δ12,14-PGA1) is a synthetic PGA1 analog. It shares common structural features with 15-deoxy-Δ12,14-PGJ2, which is a ligand for PPARγ.1 Antimitotic and antitumor activity have been reported for a similar analog,2 but there are no published reports on the biological activity of 15-deoxy-Δ12,14-PGA1 at this time.

1 Kliewer, S.A., Lenhard, J.M., Willson, T.M., et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 83 813-819 (1995).

2 Kato, T., Fukushima, M., Kurozumi, S., et al. Antitumor activity of Δ7-prostaglandin A1 and Δ12-prostaglandin J2 in vitro and in vivo. Cancer Res 46 3538-3542 (1986).

Synonyms
  • 15-deoxy-Δ12,14-PGA1
Formal Name 9-​oxo-​prosta-​10,​12Z,​14E-​trien-​1-​oic acid
CAS Number 573951-20-9
Molecular Formula C20H30O3
Formula Weight 318.5
Formulation A solution in methyl acetate
Purity >95%
λmax 324 nm
Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
CCCCC/C=C/C=C1\C=CC(=O)​C\1CCCCCCC(=O)​O

Background Reading

Kato, T., Fukushima, M., Kurozumi, S., et al. Antitumor activity of Δ7-prostaglandin A1 and Δ12-prostaglandin J2 in vitro and in vivo. Cancer Res 46 3538-3542 (1986).

Kliewer, S.A., Lenhard, J.M., Willson, T.M., et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 83 813-819 (1995).

15-deoxy-Δ12,14-Prostaglandin A1 is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $107.00 $0.00
5 mg $482.00 $0.00
10 mg $856.00 $0.00
50 mg $3,745.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

15-deoxy-Δ12,14-Prostaglandin J2
Prostaglandin A1
Prostaglandin A1 methyl ester Exclusive

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?