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(±)-Enterolactone

Cayman Chemical Item Number 10112

HPMF (CAS 78473-71-9)

(±)-Enterolactone (CAS 78473-71-9)

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Description

Diets high in fiber contain plant lignan species that may be directly responsible for some observed health benefits of these diets.1 Enterolactone is an enterobacterial breakdown product of plant lignans that is absorbed and can be measured in human serum. Enterolactone and other ligans and phytoestrogens have been associated with a reduced risk of acute coronary events, hormone-dependent cancers, and possibly osteoporosis. Recent observations have shown an inverse association between serum enterolactone levels and serum isoprostane levels.2 This association implies a protective effect against oxidative injury associated with the dietary lignans themselves, enterolactone, or some intermediate in this pathway.

1 Morton, L.W., Caccetta, R.A., Puddey, I.B., et al. Chemistry and biological effects of dietary phenolic compounds: Relevance to cardiovascular disease. Clin Exp Pharmacol Physiol 27 152-159 (2000).

2 Vanharanta, M., Voutilainen, S., Nurmi, T., et al. Association between low serum enterolactone and increased plasma F2-isoprostanes, a measure of lipid peroxidation. Atherosclerosis 160 465-469 (2002).

Synonyms
  • HPMF
Formal Name (±)-​trans-​dihydro-​3R,​4R-​bis[(3-​hydroxyphenyl)methyl]-​2(3H)-​furanone
CAS Number 78473-71-9
Molecular Formula C18H18O4
Formula Weight 298.3
Formulation A solution in ethanol
Purity ≥95%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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OC1=CC(C[C@@H]​([C@H]​(CC2=CC=CC(O)​=C2)​CO3)​C3=O)​=CC=C1

Background Reading

Morton, L.W., Caccetta, R.A., Puddey, I.B., et al. Chemistry and biological effects of dietary phenolic compounds: Relevance to cardiovascular disease. Clin Exp Pharmacol Physiol 27 152-159 (2000).

Vanharanta, M., Voutilainen, S., Nurmi, T., et al. Association between low serum enterolactone and increased plasma F2-isoprostanes, a measure of lipid peroxidation. Atherosclerosis 160 465-469 (2002).

(±)-Enterolactone is available in the following screening library:

Size Price Quantity Subtotal
1 mg $28.00 $0.00
5 mg $126.00 $0.00
10 mg $224.00 $0.00
50 mg $980.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-25. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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