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101550 CB2 Receptor Polyclonal Antibody
Cannabinoid Receptor 2
CB2 Receptor Polyclonal Antibody Workbook Links
Cayman offers a variety of analysis tools to assist you.
Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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Antigen:
human CB2 receptor sequence amino acids 20-33 (NPMKDYMILSGPQK)
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Host:
rabbit
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Application(s):
WB and IHC; other applications not tested
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The CB2 receptor is localized predominantly in peripheral tissues, including the spleen and hemopoietic cells.1 · The CB1 and CB2 receptors are G-protein coupled receptors that bind the active component of cannabis, Δ9-tetrahydrocannabinol, as well as anandamide which is an endogenous CB receptor ligand. This antibody has been raised against a sequence between the N-terminus and the first transmembrane domain of the protein of the human CB2 receptor.1 It can be used for Western blotting and immunohistochemistry applications. Conserved amino acids between the CB1 and CB2 receptors in this region are minimal thereby preventing cross-reactivity of this antibody with the CB1 receptor.2 Human and murine CB2 receptors exhibit 82% homology at the amino acid level over the complete protein.2 The CB2 receptor is localized predominantly in peripheral tissues, including the spleen and hemopoietic cells.1
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1
Munro, S., Thomas, K.L., Abu-Shaar, M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 365 61-65 (1993).
2
Shire, D., Calandra, B., Rinaldi-Carmona, M., et al. Molecular cloning, expression and function of the murine CB2 peripheral cannabinoid receptor. Biochim Biophys Acta 1307 132-136 (1996).
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Purchase 101550 CB2 Receptor Polyclonal Antibody
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-02-09.
Prices are subject to change without notice.
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