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Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.
Histone H2B (Xenopus recombinant)Cayman Chemical Item Number 10262 
Histone H2B (Xenopus recombinant)
Description
Source:
recombinant protein expressed in E. coli
·
Mr:
13.7 kDa
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A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4.1 The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core.2 Histone H2B undergoes many modifications which include acetylation, phosphorylation, ubiquitylation, and sumoylation that are important for regulation of gene transcription.1
1 Bhaumik, S.R., Smith, E., and Shilatifard, A. Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14(11) 1008-1016 (2007). 2 Tanaka, Y., Tawaramoto-Sasanuma, M., Kawaguchi, S., et al. Expression and purification of recombinant human histones. Methods 33 3-11 (2004).
Background ReadingTanaka, Y., Tawaramoto-Sasanuma, M., Kawaguchi, S., et al. Expression and purification of recombinant human histones. Methods 33 3-11 (2004). Bhaumik, S.R., Smith, E., and Shilatifard, A. Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14(11) 1008-1016 (2007). |
This product is available in custom sizes and/or larger quantities. Please contact our Sales Department for a quote or to purchase. Pricing updated 2012-05-26. Prices are subject to change without notice. To ask for assistance with one of our products please contact a Technical Support Scientist. Warning This product is not for human or veterinary use. Related ProductsShow all 23 Hide all but first 3Downloads
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins. |
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