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Histone H2B (Xenopus recombinant)Cayman Chemical Item Number 10262 
Histone H2B (Xenopus recombinant)
Description
Source:
recombinant protein expressed in E. coli
·
Mr:
13.7 kDa
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A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4.1 The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core.2 Histone H2B undergoes many modifications which include acetylation, phosphorylation, ubiquitylation, and sumoylation that are important for regulation of gene transcription.1
1 Bhaumik, S.R., Smith, E., and Shilatifard, A. Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14(11) 1008-1016 (2007). 2 Tanaka, Y., Tawaramoto-Sasanuma, M., Kawaguchi, S., et al. Expression and purification of recombinant human histones. Methods 33 3-11 (2004).
Background ReadingTanaka, Y., Tawaramoto-Sasanuma, M., Kawaguchi, S., et al. Expression and purification of recombinant human histones. Methods 33 3-11 (2004). Bhaumik, S.R., Smith, E., and Shilatifard, A. Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14(11) 1008-1016 (2007). |
This product is available in custom sizes and/or larger quantities. Please contact our Sales Department for a quote or to purchase. Pricing updated 2012-02-12. Prices are subject to change without notice. To ask for assistance with one of our products please contact a Technical Support Scientist. Warning This product is not for human or veterinary use. Related ProductsShow all 23 Hide all but first 3Downloads
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins. |
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