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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Histone H3 Trimethyl Lys9 Peptide

Cayman Chemical Item Number 10530

H3K9(Me)3 Peptide

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Description

Histone H3 undergoes many modifications including acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.1 This histone H3 peptide contains a trimethylated lysine residue at position nine which is a substrate for several of the JmjC domain-containing class of histone demethylases. JMJD2A and JMJD2D exhibit higher affinity with H3K9(Me)3 compared to H3K9(Me)2.2

1 Bhaumik, S.R., Smith, E., and Shilatifard, A. Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14(11) 1008-1016 (2007).

2 Couture, J., Collazo, E., Ortiz-Tello, P.A., et al. Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase. Nat Struct Mol Biol 14(8) 689-695 (2007).

Synonyms
  • H3K9(Me)3 Peptide
Formula Weight 1601.0
Formulation A lyophilized peptide
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere

Background Reading

Couture, J., Collazo, E., Ortiz-Tello, P.A., et al. Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase. Nat Struct Mol Biol 14(8) 689-695 (2007).

Bhaumik, S.R., Smith, E., and Shilatifard, A. Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14(11) 1008-1016 (2007).

Size Price Quantity Subtotal
1 mg $153.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-02-11. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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