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JWH 018

Cayman Chemical Item Number 10900

(CAS 209414-07-3)

JWH 018 (CAS 209414-07-3)

See more	Cannabinoids (333) Forensic Science (369) Neuroscience (725) Pain (151)

Description

JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB₂) receptor, derived from the aminoalkylindole WIN 55212-2. The K_i values for binding central cannabinoid (CB₁) and CB₂ receptors are 9.0 and 2.94 nM, respectively, for a CB₁:CB₂ ratio of 3.06.¹ Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55212-2 when tested in rats.²

1 Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB₁ and CB₂ receptor binding. Drug Alcohol Depend 60 133-140 (2000).

2 Wiley, J.L., Compton, D.R., Dai, D., et al. Structure-activity relationships of indole- and pyrrole-derived cannabinoids. J Pharmacol Exp Ther 285(3) 995-1004 (1998).

Formal Name	(1-pentyl-1H-indol-3-yl)-1-naphthalenyl-methanone
CAS Number	209414-07-3
Molecular Formula	C₂₄H₂₃NO
Formula Weight	341.5
Formulation	A solution in methanol
Purity	≥98%
λ_max	219, 246 nm
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12

Size	Price	Quantity	Subtotal
5 mg	$51.00		$0.00
10 mg	$96.00		$0.00
25 mg	$225.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-26. Prices are subject to change without notice.

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Featured Products	Mojo
JWH 018 (solution) Selective agonist of the CB2 receptor	47.491561336422
JWH 073 Selective agonist of the CB1 receptor	35.953065587533
JWH 073 (solution) Selective agonist of the CB1 receptor	42.977244992795
JWH 200 Potent cannabinoid receptor agonist	23.047589726815
JWH 200 (solution) Potent cannabinoid receptor agonist	42.655236723869
(±)-CP 47,497 A potent CB1 receptor agonist	34.382032339974
(±)-CP 47,497 (solution) A potent CB1 receptor agonist	49.485946899938
(±)-CP 47,497-C8-homolog Exclusive A potent bicyclic CB analog	33.614779595787
(±)-CP 47,497-C8-homolog (solution) Exclusive A potent bicyclic CB analog	43.928671821398
HU-210 A potent synthetic cannabinoid	45.112620856353
HU-210 (solution) A potent synthetic cannabinoid	30.987411207576
Cannabidiol A neuroprotective phenolic compound from marijuana	31.817340173638
Cannabidiol (solution) A neuroprotective phenolic compound from marijuana	45.111998995479
Synthetic Cannabinoid HPLC Mixture II Contains a selection of the most common JWH-, CP-, and HU-series CB receptor agonists	44.388457144890

Related Products

JWH 018 2'-naphthyl isomer Exclusive

JWH 018 2'-naphthyl-N-(1,1-dimethylpropyl) isomer New Exclusive

JWH 018 2’-naphthyl-N-(1-ethylpropyl) isomer New Exclusive

JWH 018 2'-naphthyl-N-(2-methylbutyl) isomer Exclusive

JWH 018 adamantyl carboxamide New Exclusive

JWH 018 N-(1,1-dimethylpropyl) isomer Exclusive

JWH 018 N-(1-ethylpropyl) isomer New Exclusive

(±)-JWH 018 N-(2-hydroxypentyl) metabolite New

(±)-JWH 018 N-(3-hydroxypentyl) metabolite

JWH 018 N-(4,5-epoxypentyl) analog

(−)-JWH 018 N-(4-hydroxypentyl) metabolite New

(+)-JWH 018 N-(4-hydroxypentyl) metabolite New

(±)-JWH 018 N-(4-hydroxypentyl) metabolite Exclusive

JWH 018 N-(5-bromopentyl) analog New

JWH 018 N-(5-chloropentyl) analog New

JWH 018 N-(5-hydroxypentyl) metabolite-d₅ Exclusive

JWH 018 (solution)

JWH 020 Exclusive

JWH 073 2-methylnaphthyl analog Exclusive

JWH 122 N-(5-hydroxypentyl) metabolite Exclusive

JWH 147 New

JWH 175 New Exclusive

JWH 200 7-hydroxyindole metabolite

JWH 250 N-(5-hydroxypentyl) metabolite-d₅ New Exclusive

JWH 307 New

JWH 309 New Exclusive

RCS-4 3-methoxy isomer Exclusive

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