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JWH 073

Cayman Chemical Item Number 10904

(CAS 208987-48-8)

JWH 073 (CAS 208987-48-8)

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Description

JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23.1 Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55212-2 when tested in rats.2

1 Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend 60 133-140 (2000).

2 Wiley, J.L., Compton, D.R., Dai, D., et al. Structure-activity relationships of indole- and pyrrole-derived cannabinoids. J Pharmacol Exp Ther 285(3) 995-1004 (1998).

Formal Name (1-​butyl-​1H-​indol-​3-​yl)-​1-​naphthalenyl-​methanone
CAS Number 208987-48-8
Molecular Formula C23H21NO
Formula Weight 327.4
Formulation A crystalline solid
Purity ≥97%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCn1cc(C(=O)​c2cccc3ccccc23)​c2ccccc12
Size Price Quantity Subtotal
5 mg $41.00 $0.00
10 mg $77.00 $0.00
25 mg $180.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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This product requires special processing and/or additional information before it can be shipped. A Customer Service representative will contact you within 24 hours of receipt of your order.

Warning This product is not for human or veterinary use.

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JWH 073 2'-naphthyl isomer Exclusive
JWH 073 2'-naphthyl-N-(1,1-dimethylethyl) isomer New Exclusive
JWH 073 2'-naphthyl-N-(1-methylpropyl) isomer Exclusive
JWH 073 2'-naphthyl-N-(2-methylpropyl) isomer Exclusive
JWH 073 4-hydroxyindole metabolite
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JWH 073 5-hydroxyindole metabolite Exclusive
JWH 073 6-hydroxyindole metabolite Exclusive
JWH 073 7-hydroxyindole metabolite Exclusive
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JWH 073 N-(1,1-dimethylethyl) isomer New Exclusive
JWH 073 N-(1-methylpropyl) isomer Exclusive
JWH 073 N-(2-methylpropyl) isomer Exclusive
(±)-JWH 073 N-(3-hydroxybutyl) metabolite-d5 Exclusive
JWH 073 N-(4-hydroxybutyl) metabolite Exclusive
JWH 073 N-(4-hydroxybutyl) metabolite-d5 Exclusive
JWH 073 N-butanoic acid metabolite Exclusive
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RCS-4
RCS-8
(R)-(−)-JWH 073 N-(3-hydroxybutyl) metabolite
(S)-(+)-JWH 073 N-(3-hydroxybutyl) metabolite
(+)WIN 55212-2 (mesylate)
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