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AM2233

Cayman Chemical Item Number 11008

(CAS 444912-75-8)

AM2233 (CAS 444912-75-8)

See more	Cannabinoids (333) Forensic Science (369) Neuroscience (725)

Description

AM2233 is a full agonist of the central cannabinoid (CB₁) receptor (K_i = 2.8 nM).¹ Most of the affinity towards the CB₁ receptor resides within the (R)-enantiomer of AM2233, which exhibits a K_i value of 0.2 nM and has ~8-fold higher affinity for CB₁ compared to WIN 55,212-2 (K_i = 1.6 nM).¹ AM2233 was developed for use as a selective radioligand for mapping the distribution of the CB₁ receptor in the brain.¹ Recently, however, AM2233 has received attention as a cannabimimetic acquired for recreational use as a “legal high” replacement for restricted substances. This compound is intended for forensic and research applications.

1 Deng, H., Gifford, A.N., Zvonok, A.M., et al. Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB₁ cannabinoid receptor. J Med Chem 48 6386-6392 (2005).

Formal Name	(2-iodophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-methanone
CAS Number	444912-75-8
Molecular Formula	C₂₂H₂₃IN₂O
Formula Weight	458.3
Formulation	A crystalline solid
Purity	≥98%
λ_max	213, 250, 314 nm
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard O=C(C1=C(I)C=CC=C1)C2=CN(CC3N(C)CCCC3)C4=CC=CC=C42

Size	Price	Quantity	Subtotal
1 mg	$14.00		$0.00
5 mg	$69.00		$0.00
10 mg	$139.00		$0.00
25 mg	$298.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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	Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
	For ChemStation-searchable GCMS spectra of many of Cayman’s emerging forensic drug standards see the Cayman Spectral Library (CSL).

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