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Prostaglandin B₁

Cayman Chemical Item Number 11110

PGB₁ (CAS 13345-51-2)

Prostaglandin B1 (CAS 13345-51-2)

See more	Prostaglandins (517)

Description

PGB₁ is a non-enzymatic dehydration product of PGE₁ resulting from treatment with strong base. Oligomers of PGB₁ are known to exhibit antioxidant and ionophoric activity.^1,2,3

1 Uribe, S., Ohnishi, S.T., Israelite, C., et al. Calcium ionophoretic activity of chemically synthesized oligomeric derivatives of prostaglandin B₁. Biochim Biophys Acta 924 87-98 (1987).

2 Ohnishi, S.T., and Devlin, T.M. Calcium ionophore activity of a prostaglandin B₁ derivative (PGBχ). Biochem Biophys Res Commun 89 240-245 (1979).

3 Hamberg, M. Metabolism of prostaglandin in rat liver mitochondria. Eur J Biochem 6 135-146 (1968).

Synonyms	PGB1
Formal Name	9-oxo-15S-hydroxy-prosta-8(12),13E-dien-1-oic acid
CAS Number	13345-51-2
Molecular Formula	C₂₀H₃₂O₄
Formula Weight	336.5
Formulation	A crystalline solid
Purity	>98%
λ_max	278 nm
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard O=C1C(CCCCCCC(O)=O)=C(/C=C/[C@@H](O)CCCCC)CC1

Background Reading

Devlin, T.M., Krupinski-Olsen, R., Uribe, S., et al. Effect of oligomeric derivatives of prostaglandin B₁ on oxidative phosphorylation and their Ca2+ ionophoretic activity. Biochem Biophys Res Commun 137 215-221 (1986).

Uribe, S., Ohnishi, S.T., Israelite, C., et al. Calcium ionophoretic activity of chemically synthesized oligomeric derivatives of prostaglandin B₁. Biochim Biophys Acta 924 87-98 (1987).

Ohnishi, S.T., and Devlin, T.M. Calcium ionophore activity of a prostaglandin B₁ derivative (PGBχ). Biochem Biophys Res Commun 89 240-245 (1979).

Hamberg, M. Metabolism of prostaglandin in rat liver mitochondria. Eur J Biochem 6 135-146 (1968).

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Prostaglandin B1 is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
1 mg	$19.00		$0.00
5 mg	$86.00		$0.00
10 mg	$152.00		$0.00
50 mg	$665.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Prostaglandin B1