Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday.
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Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.
Zearalenone is a mycotoxin produced by fungi in food and animal feeds.1 Although of low acute toxicity, zearalenone activates estrogen receptors, alters hormone levels, and hasten pre-pubertal development, especially in pigs.2,3 While pre-pubertal animals appear to be more sensitive to zearalenone than older animals, the toxin can cause uterine, rectal, and vaginal prolapse, abortion, and infertility in older animals.4 Evidence for zearalenone effects have been observed in a wide variety of animals, including man.4,5,2
1
Zinedine, A., Soriano, J.M., Moltó, J.C., et al. Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An oestrogenic mycotoxin. Food Chem Toxicol451-18(2007).
2
Richard, J.L. Some major mycotoxins and their mycotoxicoses - An overview. Int J Food Microbiol1193-10(2007).
3
Tiemann, U., and Dänicke, S. In vivo and in vitro effects of the mycotoxins zearalenone and deoxynivalenol on different non-reproductive and reproductive organs in female pigs: A review. Food Addit Contam24(3)306-314(2007).
4
Caloni, F., and Cortinovis, C. Effects of fusariotoxins in the equine species. Vet J186157-161(2010).
5
Massart, F., and Saggese, G. Oestrogenic mycotoxin exposures and precocious pubertal development. Int J Androl33369-376(2010).