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Beauvericin New

Cayman Chemical Item Number 11426

(CAS 26048-05-5)

Beauvericin (CAS 26048-05-5)

See more	Cell Biology (303) Toxicology (28)

Description

Beauvericin is a mycotoxin originally derived from B. bassiana, a common fungal parasite of arthropods. It is also produced by the fungus Fusarium, a pathogen of insects and plants.¹ Beauvericin is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 μM.² In mammalian cells, beauvericin induces apoptosis with an IC₅₀ value of 4.5 μM.^1,3

1 Logrieco, A., Moretti, A., Castella, G., et al. Beauvericin production by Fusarium species. Appl Environ Microbiol 64(8) 3084-3088 (1998).

2 Calo, L., Fornelli, F., Nenna, S., et al. Beauvericin cytotoxicity to the invertebrate cell line SF-9. J Appl Genet 44(4) 515-520 (2003).

3 Tonshin, A.A., Teplova, V.V., Andersson, M.A., et al. The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis. Toxicology 276 49-57 (2010).

Formal Name	cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl]
CAS Number	26048-05-5
Molecular Formula	C₄₅H₅₇N₃O₉
Formula Weight	783.0
Formulation	A crystalline solid
Purity	≥98%
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard O=C([C@H](CC1=CC=CC=C1)N(C([C@@H](C(C)C)OC([C@H](CC2=CC=CC=C2)N(C)C([C@@H](C(C)C)OC([C@H](CC3=CC=CC=C3)N4C)=O)=O)=O)=O)C)O[C@H](C(C)C)C4=O

Size	Price	Quantity	Subtotal
1 mg	$24.00		$0.00
5 mg	$108.00		$0.00
10 mg	$192.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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