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Prostaglandin D₁

Cayman Chemical Item Number 12000

PGD₁ (CAS 17968-82-0)

Prostaglandin D1 (CAS 17968-82-0)

See more	Prostaglandins (513)

Description

Prostaglandin D₁ (PGD₁) is the theoretical D-series metabolite of DGLA, but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC₅₀ value of 320 ng/ml, about 1/10 as potent as PGD₂.¹

1 Bundy, G.L., Morton, D.R., Peterson, D.C., et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. J Med Chem 26 790-799 (1983).

Synonyms	PGD1
Formal Name	9α,15S-dihydroxy-11-oxo-prost-13E-en-1-oic acid
CAS Number	17968-82-0
Molecular Formula	C₂₀H₃₄O₅
Formula Weight	354.5
Formulation	A crystalline solid
Purity	>98%
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1CCCCCCC(=O)O

Background Reading

Bundy, G.L., Morton, D.R., Peterson, D.C., et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. J Med Chem 26 790-799 (1983).

Goh, Y., Nakajima, M., Azuma, I., et al. Effects of prostaglandin D₂ and its analogues on intraocular pressure in rabbits. Jpn J Ophthamol 32 471-480 (1988).

Jones, R.L. Cardiovascular actions of prostaglandins D and E in the sheep: Evidence for two distinct receptors. Adv Prostaglandin Thromboxane Res 1 221-231 (1976).

Prostaglandin D1 is available in the following screening libraries:

Size	Price	Quantity	Subtotal
1 mg	$46.00		$0.00
5 mg	$207.00		$0.00
10 mg	$368.00		$0.00
100 mg	$2,760.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Prostaglandin D1