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Prostaglandin D₂ Ethanolamide

Cayman Chemical Item Number 12012

PGD₂-EA (CAS 398138-28-8)

Prostaglandin D2 Ethanolamide (CAS 398138-28-8)

See more	Prostaglandins (513) Neuroscience (654)

Description

Anandamide (AEA) is a substrate for cyclooxygenase and the conversion of this fatty acid amide to PGE₂ compounds has been demonstrated in vitro.¹ Conversion into any of the other primary PGs is also theoretically possible. In addition, these compounds are intresting analogs of the parent PG and may have useful pharmacologic uses. PGD₂-EA is one of these analogs.

1 Gupta, R.A., Sarra, P., Mueller, E., et al. Peroxisome proliferator-activated receptor γ-mediated differentiation. A mutation in colon cancer cells reveals divergent and cell type-specific mechanisms. J Biol Chem 278(25) 22669-22677 (2003).

Synonyms	PGD2-EA
Formal Name	N-(2-hydroxyethyl)-11-oxo-9α,15S-dihydroxy-prosta-5Z,13E-dien-1-amide
CAS Number	398138-28-8
Molecular Formula	C₂₂H₃₇NO₅
Formula Weight	395.5
Formulation	A solution in ethanol
Purity	>96%
Stability	1 year
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1C/C=C\CCCC(=O)NCCO

Background Reading

Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. J Biol Chem 277(47) 44877-44885 (2002).

Prostaglandin D2 Ethanolamide is available in the following screening libraries:

Size	Price	Quantity	Subtotal
1 mg	$64.00		$0.00
5 mg	$288.00		$0.00
10 mg	$512.00		$0.00
50 mg	$2,240.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Batch-specific Information

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Prostaglandin D2 Ethanolamide