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Prostaglandin E1 Ethanolamide

Cayman Chemical Item Number 13012

PGE1-EA; Alprostadil Ethanolamide (CAS 210976-81-1)

Prostaglandin E1 Ethanolamide (CAS 210976-81-1)

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Description

Prostaglandin E1 ethanolamide (PGE1-EA) is the ethanolamine-amide analog of PGE1. Conversion of AEA, the ethanolamide of arachidonic acid, to PGE2-EA has been demonstrated in vitro.1,2 It is not established whether this conversion occurs in whole animals, nor has the pharmacology of the resultant prostaglandin ethanolamides been rigorously studied.

1 Yu, M., Ives, D., and Ramesha, C.S. Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2. J Biol Chem 272 21181-21186 (1997).

2 Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. J Biol Chem 277(47) 44877-44885 (2002).

Synonyms
  • PGE1-EA
  • Alprostadil Ethanolamide
Formal Name N-​(2-​hydroxyethyl)-​9-​oxo-​11α,​15S-​dihydroxy-​prost-​13E-​en-​1-​amide
CAS Number 210976-81-1
Molecular Formula C22H39NO5
Formula Weight 397.6
Formulation A crystalline solid
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCC(O)​/C=C/[C@H]​1C(O)​CC(=O)​C1CCCCCCC(=O)​NCCO

Background Reading

Yu, M., Ives, D., and Ramesha, C.S. Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2. J Biol Chem 272 21181-21186 (1997).

Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. J Biol Chem 277(47) 44877-44885 (2002).

Prostaglandin E1 Ethanolamide is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $46.00 $0.00
5 mg $207.00 $0.00
10 mg $368.00 $0.00
50 mg $1,610.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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