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4-(n-nonyl) Benzeneboronic Acid

Cayman Chemical Item Number 13140

(CAS 256383-45-6)

4-(n-nonyl) Benzeneboronic Acid (CAS 256383-45-6)

See more	Cannabinoids (296) Inhibitors (493) Endocrinology (335) Neuroscience (654)

Description

Fatty acid amide hydrolase (FAAH) is the primary enzyme responsible for the hydrolysis of the endocannabinoid arachidonoyl ethanolamide (AEA). 4-(n-Nonyl)benzeneboronic acid is a potent inhibitor of FAAH, with an IC₅₀ of 9.1 nM.¹ It is also able to inhibit monoacylglycerol lipase (MAGL), which hydrolyzes 2-arachidonoyl glycerol (2-AG), but at ~1000-fold higher concentration (IC₅₀ = 7.9 μM).¹

1 Minkkilä, A., Saario, S.M., Käsnänen, H., et al. Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase. J Med Chem 51 7057-7060 (2008).

Formal Name	B-(4-nonylphenyl)-boronic acid
CAS Number	256383-45-6
Molecular Formula	C₁₅H₂₅BO₂
Formula Weight	248.2
Formulation	A crystalline solid
Purity	≥98%
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCCCc1ccc(cc1)B(O)O

Background Reading

Minkkilä, A., Saario, S.M., Käsnänen, H., et al. Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase. J Med Chem 51 7057-7060 (2008).

Size	Price	Quantity	Subtotal
100 mg	$14.00		$0.00
250 mg	$33.00		$0.00
500 mg	$63.00		$0.00
1 g	$112.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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