1 Chou, C.J., Herman, D., and Gottesfeld, J.M. Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases. J Biol Chem 283(51) 35402-35409 (2008).

2 Rai, M., Soragni, E., Jenssen, K., et al. HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model. PLoS One 3(4) (2008).

3 Herman, D., Jenssen, K., Burnett, R., et al. Histone deacetylase inhibitors reverse gene silencing in Friedreich’s ataxia. Nat Chem Biol 2(10) 551-558 (2006).

4 Thomas, E.A., Coppola, G., Desplats, P.A., et al. The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington’s disease transgenic mice. Proc Natl Acad Sci USA 105(40) 15564-15569 (2008).

Thomas, E.A., Coppola, G., Desplats, P.A., et al. The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington’s disease transgenic mice. Proc Natl Acad Sci USA 105(40) 15564-15569 (2008).

Chou, C.J., Herman, D., and Gottesfeld, J.M. Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases. J Biol Chem 283(51) 35402-35409 (2008).

Rai, M., Soragni, E., Jenssen, K., et al. HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model. PLoS One 3(4) (2008).

Herman, D., Jenssen, K., Burnett, R., et al. Histone deacetylase inhibitors reverse gene silencing in Friedreich’s ataxia. Nat Chem Biol 2(10) 551-558 (2006).

Pimelic Diphenylamide 106 is available in the following screening libraries:

• Bio-active Lipid I Screening Library (96-Well)
• Epigenetics Screening Library (96-Well)