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(±)-CP 47,497-C8-homolog (solution) Exclusive

Cayman Chemical Item Number 13216

CAY10596; Cannabicyclohexanol (CAS 70434-92-3)

(±)-CP 47,497-C8-homolog (solution) (CAS 70434-92-3)

See more	Cannabinoids (333) Forensic Science (369) Neuroscience (725) Pain (151)

Description

(±)-CP 47,497-C8-homolog is a bicyclic cannabinoid (CB) analog that avidly binds the CB₁ receptor (K_i = 0.83 nM) and shows high antinociceptive activity.¹ It is ten-fold more potent than Δ⁹-tetrahydrocannabinol in analgesic, motor depressant, anticonvulsant, and hypothermic effects in mice.²

1 Melvin, L.S., Milne, G.M., Johnson, M.R., et al. Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: Studies of bicyclic cannabinoid analogs. Mol Pharmacol 44 1008-1015 (1993).

2 Compton, D.R., Johnson, M.R., Melvin, L.S., et al. Pharmacological profile of a series of bicyclic cannabinoid analogs: Classification as cannabimimetic agents. J Pharmacol Exp Ther 260(1) 201-209 (1992).

Synonyms	CAY10596 Cannabicyclohexanol
Formal Name	rel-2-[(1S,3R)-3-hydroxycyclohexyl]-5-(2-methylnonan-2-yl)phenol
CAS Number	70434-92-3
Molecular Formula	C₂₂H₃₆O₂
Formula Weight	332.5
Formulation	A solution in methanol
Purity	≥98%
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard O[C@H]1C[C@@H](C2=CC=C(C(C)(C)CCCCCCC)C=C2O)CCC1

Background Reading

Melvin, L.S., Milne, G.M., Johnson, M.R., et al. Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: Studies of bicyclic cannabinoid analogs. Mol Pharmacol 44 1008-1015 (1993).

Compton, D.R., Johnson, M.R., Melvin, L.S., et al. Pharmacological profile of a series of bicyclic cannabinoid analogs: Classification as cannabimimetic agents. J Pharmacol Exp Ther 260(1) 201-209 (1992).

(±)-CP 47,497-C8-homolog (solution) is available in the following screening library:

Cannabinoid Agonist Screening Library (96-Well)

Size	Price	Quantity	Subtotal
5 mg	$55.00		$0.00
10 mg	$105.00		$0.00
25 mg	$248.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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