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Neurodazine Exclusive

Cayman Chemical Item Number 13224

(CAS 937807-66-4)

Neurodazine (CAS 937807-66-4)

See more	Alzheimer's Research (44) Gene Regulation (173) Parkinson's Research (18)

Description

Neurodazine induces neuronal differentiation in skeletal muscle cells.¹ In murine C2C12 myoblasts, neurodazine (2 μM for seven days) upregulated the expression of neuron-specific enolase (NSE), neurofilament 200 (NF200), synapsin, and other neuronal markers. Neurodazine similarly upregulated NSE and NF200 in human skeletal muscle fibers, indicating efficacy in mature muscle as well as in myoblasts.

1 Wiliams, D.R., Lee, M., Song, Y., et al. Synthetic small molecules that induce neurogenesis in skeletal muscle. J Am Chem Soc 129 9258-9259 (2007).

Formal Name	2-[5-(3-chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
CAS Number	937807-66-4
Molecular Formula	C₂₇H₂₁ClN₂O₃
Formula Weight	456.9
Formulation	A crystalline solid
Purity	≥98%
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard COc1ccc(cc1)c1[nH]c(nc1c1ccc(OC)cc1)c1ccc(o1)c1cccc(Cl)c1

Background Reading

Wiliams, D.R., Lee, M., Song, Y., et al. Synthetic small molecules that induce neurogenesis in skeletal muscle. J Am Chem Soc 129 9258-9259 (2007).

Neurodazine is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
5 mg	$77.00		$0.00
10 mg	$146.00		$0.00
25 mg	$347.00		$0.00
50 mg	$616.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

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