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CAY10616 Exclusive

Cayman Chemical Item Number 13291

(CAS 586410-08-4)

CAY10616 (CAS 586410-08-4)

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Description

Resveratrol is a natural polyphenolic antioxidant that has anti-cancer properties. CAY10616 is an analog of resveratrol which is a potent inducer of apoptosis in promyelocytic leukemia HL-60 cells (IC50 = 40 nM versus 50 μM for resveratrol).1 In addition, CAY10616 induces apoptosis (IC50 = 30 nM) in HL60R, a cell line derived from HL-60 that expresses a multidrug-resistance phenotype (resistant to daunorubicin, etoposide, and citarabine).1

1 Roberti, M., Pizzirani, D., Simoni, D., et al. Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. J Med Chem 46 3546-3554 (2003).

Formal Name 5-​[(1Z)-​2-​(3,​5-​dimethoxyphenyl)ethenyl]-​2-​methoxy-​phenol
CAS Number 586410-08-4
Molecular Formula C17H18O4
Formula Weight 286.3
Formulation A solution in methyl acetate
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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COc1cc(\C=C\c2ccc(OC)​c(O)​c2)​cc(OC)​c1

Background Reading

Roberti, M., Pizzirani, D., Simoni, D., et al. Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. J Med Chem 46 3546-3554 (2003).

CAY10616 is available in the following screening library:

Size Price Quantity Subtotal
1 mg $21.00 $0.00
5 mg $95.00 $0.00
10 mg $168.00 $0.00
25 mg $368.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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